Application

The antibody is recommended to use in various immunological techniques, including ELISA, dot blot, immunoprecipitation, and immunoblot . The antibody reacts against native and denatured (non-reduced) human haptoglobin but does not recognize the haptoglobin under reducing conditions.

General description

Haptoglobin, also known as HP, is a serum α2-glycoprotein that exists as a tetramer, composed of two smaller identical alpha (α) chains and two larger identical beta (β) chains. The α-chains are linked to each other by a disulfide bond and each β-chain is similarly linked to an α-chain.Monoclonal Anti-Haptoglobin specifically recognizes the three types of human haptoglobin (types 1-1, 2-1, and 2-2) The antibody recognizes both purified and haptoglobin in human serum, and shows no crossreactivity with human IgG, transferrin, C-reactive protein, α-1-acid glycoprotein, albumin, hemoglobin, or bovine, goat and sheep serum haptoglobin.

Immunogen

purified haptoglobin from pooled human plasma

Other Notes

This product is for R&D use only, not for drug, household, or other uses.

Physical form

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide as preservative.